Nanotechnology: Anti-Cancer Therapy For Breast Cancer – Part 3

A fine tuning between size, shape and surface physico-chemical properties can lead to a precise control of the particulate behavior in terms of margination dynamics, vascular adhesion and internalization, and mathematical modeling can lead to define Design Maps, which can help predict particle behavior and drive particle development. These study clearly suggests that the geometry of the delivery carriers is one of critical determinant for their behavior in the circulation. In conclusion, it is evident that anti-cancer therapy certainly needs a breakthrough to eradicate cancer related death. Nanotechnology is one of the growing fields in medical science with a promise to address long standing clinical issues. There are an overwhelming number of distinct nanoparticles that have been developed which vary with respect to many properties, such as particle size, shape, charge, surface modification, and drug payload/therapeutic effect. The future challenges in the successful clinical applications of nanotechnology based drug delivery are not the lack of novel technologies, it is rather the need to identify favorable physio-chemical properties that will allow injectable nanovectors to overcome multiple barriers.

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